University, Aarhus | Denmark
Our research group determines crystal structures of large single proteins, protein-protein complexes, and protein-RNA complexes. These are supplemented with small angle X-ray scattering measurements and cryo-EM reconstructions. In particular, we study complement proteins with key functions in the mammalian innate immune system. Another research theme is structure determination of helicases catalysing rearrangements of protein-RNA complexes.
Keywords: Crystallography / protein structure / innate immunity / complement