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EMBO Member

Gregers Rom Andersen

University, Aarhus | Denmark

EMBO 2011

Structure determination of large macromolecules

Our research group determines crystal structures of large single proteins, protein-protein complexes, and protein-RNA complexes. These are supplemented with small angle X-ray scattering measurements and cryo-EM reconstructions. In particular, we study complement proteins with key functions in the mammalian innate immune system. Another research theme is structure determination of helicases catalysing rearrangements of protein-RNA complexes.

Keywords: Crystallography / protein structure / innate immunity / complement

Subject area(s): Immunology | RNA | Structural Biology & Biophysics