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EMBO Member

Guido Kroemer

Centre de Recherche des Cordeliers, Paris | France

EMBO 2000

Cell death, autophagy & cancer immunosurveillance

Kroemer, an international leader in cell death research, discovered that apoptosis and necrosis is ignited by mitochondrial membrane permeabilization. He also pioneered the revolutionary concept that anticancer chemotherapies and radiotherapies are particularly successful if they induce immunogenic cell stress and death, thereby converting tumors into therapeutic vaccines.

Keywords: Anticancer immunosurveillance / apoptosis / autophagy / necrosis / mitochondria / microbiome

Subject area(s): Differentiation & Death | Immunology | Molecular Medicine