Centre de Recherche des Cordeliers, Paris | France
Kroemer, an international leader in cell death research, discovered that apoptosis and necrosis is ignited by mitochondrial membrane permeabilization. He also pioneered the revolutionary concept that anticancer chemotherapies and radiotherapies are particularly successful if they induce immunogenic cell stress and death, thereby converting tumors into therapeutic vaccines.
Keywords: Anticancer immunosurveillance / apoptosis / autophagy / necrosis / mitochondria / microbiome
Subject area(s): Differentiation & Death | Immunology | Molecular Medicine