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EMBO Member

Guy R. Cornelis

Crupet (Assesse) | Belgium

EMBO 1998

Pathogenesis of Capnocytophaga canimorsus

My group studies the pathogenesis of Capnocytophaga canimorsus, Gram-negative bacteria from the normal oral flora of dogs, which cause rare but severe infections in humans that have been bitten or simply licked. We pay particular attention to a new kind of feeding complexes, some of them specialized in deglycosylating glycoproteins from the host. This allows C. canimorsus to feed by grazing oligosaccharides at the surface of human cells.

Keywords: Type III secretion / injectisome / Yersinia / Capnocytophaga canimorsus / bacterial surface

Subject area(s): Membranes & Transport | Microbiology, Virology & Pathogens | Proteins & Biochemistry