Tissue regeneration and cancer resistance
Based on our newly identified functions of cytosolic innate immune sensors in maintaining tissue homoestasis after allo-HSCT and tumor immunosurveillance, the scientific focus of our laboratory is currently centered around two topics: (i) regenerative responses after allogeneic hematopoietic stem cell transplantation; (ii) mechanisms of immune evasion caused by aberrant innate nucleic acid receptor signaling in tumor cells / tumor microenvironment.
Keywords
Innate immune signaling / cancer immunology & resistance / allogeneic stem cell transplantation / intestinal stem cells