EMBO Member

Ilan Davis

University of Oxford | United Kingdom

EMBO 2010

mRNA localisation in oocytes and neurons

We are studying the molecular mechanism of mRNA localisation and translational regulation in Drosophila oocytes and the neuromuscular junction. These post-transcriptional modes of regulation of gene expression target protein production. They are essential for setting up the primary embryonic axes in the oocyte and for allowing rapid local activation of protein production during synaptic plasticity.

Keywords: mRNA localisation / local translation / Drosophila / neuromuscular junction / microtubule motors

Subject area(s): Development | Neuroscience | RNA