University of Oxford | United Kingdom
We are studying the molecular mechanism of mRNA localisation and translational regulation in Drosophila oocytes and the neuromuscular junction. These post-transcriptional modes of regulation of gene expression target protein production. They are essential for setting up the primary embryonic axes in the oocyte and for allowing rapid local activation of protein production during synaptic plasticity.
Keywords: mRNA localisation / local translation / Drosophila / neuromuscular junction / microtubule motors