Tumour microenvironment and metastatic progression
My group seeks to understand how local and systemic perturbations caused by cancer cells drive tumour growth and metastatic progression. To achieve this goal, we develop and use unbiased approaches in animal models, including a range of genetic tracing, proximity labelling, bioengineered tissues as well as ex vivo 3D co-cultures and organoid systems with primary cells.
Keywords
Tumour microenvironment / neutrophils / metastasis / stem cells / mouse model