Hox control of development in Drosophila
My group investigates the role of Hox proteins in cell fate specification, differentiation, tissue communication, and homeostasis. These conserved proteins control body part identities along the anterior-posterior axis in animals. We employ genomic, genetic, molecular, biochemical, and proteomic techniques, alongside computational analyses and simulations, to uncover how closely related Hox proteins perform their specific functions in vivo.
Keywords
Hox genes / transcriptional control / Drosophila development / cellular plasticity / stem cell control / cell fate specification / tissue communication