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EMBO Member

Irene Miguel-Aliaga

Francis Crick Institute, London | United Kingdom

EMBO 2017

The sex, geometry and plasticity of organs

Our lab explores how adult organs, especially the gut, remodel in response to experience. We investigate how intestinal cells sense cues, coordinate organ-wide changes and signal to other tissues. Using experimental and computational approaches across flies, mice and humans, we study sex and reproductive differences in gut form and function to illuminate the mechanisms linking gut plasticity to whole-body physiology and disease.

Keywords: Intestine / physiology / sex differences / enteric neurons / nutrition / reproduction / development / Drosophila

Subject area(s): Cellular Metabolism | Development | Neuroscience

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