The molecular basis of immunity
Our lab investigates the molecular bases underpinning protective and aberrant immunity. This includes studying how T cell receptors (TCRs) and Natural Killer cells recognise peptides presented by molecules encoded by the Major Histocompatibility Complex; and how TCRs recognise lipids and metabolites presented by the CD1 family and MR1, respectively.
Keywords
Cellular immunity / structural immunology / T cell antigen receptor / major histocompatibility complex molecule / aberrant immunity