From genomic variation to molecular mechanism
My research interest is uncovering determinants for the formation and selection of genetic variation, especially structural variation, in the germline and in cancer. My group employs experiments and computational approaches, and we perform research projects within my group and within consortia including the 1000 Genomes Project, and the Pan-Cancer Analysis of Whole Genomes Project that I am co-leading.
Keywords
Structural variation / human genome sequencing / population-scale sequencing / cancer genomics / chromothripsis / imaging / AI