
EMBO Young Investigator
Jan Philipp Junker
YIP 2020–2024
MDC, Berlin, Germany
Cell fate decisions and development variability
We study cell fate decisions in health and disease by using and developing methods in single-cell genomics, including approaches for high-throughput lineage tracing. Our main scientific questions are related to variability of cell fate decisions: How variable is unperturbed vertebrate embryonic development? How are external perturbations corrected during development? Which mechanisms allow adult organs to regenerate after injury?
Keywords
Single-cell genomics / lineage tracing / zebrafish / development / regeneration / variability / computational biology