My group is involved in theoretical and experimental research on macromolecular structures. Theoretical research involves the development of bioinformatics software, structure prediction and modeling of RNA and RNA-protein complexes. In experimental studies we combine X-ray crystallography, SAXS, structure probing and other low-resolution methods. We also engineer proteins to obtain enzymes with new features, e.g. altered substrate specificities.
Keywords: Bioinformatics / molecular modeling / macromolecular complexes / RNA structure / epitranscriptomics / RNA-protein interactions / RNA methyltransferases / protein engineering