RNA-binding proteins in health and disease
Our research focuses on the role of RNA-binding proteins (RNABPs) in gene expression at different levels during the RNA processing cascade from splicing in the nucleus to translation in the cytoplasm. We study post-transcriptional mechanisms that regulate gene expression with special emphasis on three RNA processing events: alternative splicing regulation, nonsense-mediated decay (NMD) and microRNA (miRNA) biogenesis and function.
Keywords
RNA-binding proteins / RNA processing / alternative splicing / non-sense mediated decay (NMD) / microRNAs