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EMBO Young Investigator

Jean-Léon Maître

Institut Curie, Paris | France

YIP 2020–2024

Mechanics of mammalian development

We want to understand how the mammalian embryo shapes itself. For this, we study how the forces that deform the embryo are generated. Usual suspects are the cytoskeleton, adhesion molecules and intercellular fluid. We use microscopy to observe the deformations, biophysical tools to measure the forces, and genetics to perturb them.

Keywords: Morphogenesis / cell and tissue mechanics / adhesion / cytoskeleton / biofluid dynamics

Subject area(s): Cell & Tissue Architecture | Development | Structural Biology & Biophysics