
Mechanics of mammalian development
We want to understand how the mammalian embryo shapes itself. For this, we study how the forces that deform the embryo are generated. Usual suspects are the cytoskeleton, adhesion molecules and intercellular fluid. We use microscopy to observe the deformations, biophysical tools to measure the forces, and genetics to perturb them.
Keywords
Morphogenesis / cell and tissue mechanics / adhesion / cytoskeleton / biofluid dynamics