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Portrait of Jens C. Brüning

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Jens C. Brüning

EMBO 2012

Universität, Köln, Germany

CNS-dependent regulation of metabolism

Our research focusses on elucidating the CNS-dependent regulation of energy and glucose metabolism through the use of genetically modified mice. These studies revealed a previously unappreciated role for insulin action in the central nervous system (CNS) to control organismal glucose homeostasis and insulin sensitivty.

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Obesity / energy homeostasis / insulin resistance / CNS insulin action / insulin signalling in the brain / fatty acid metabolism

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