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EMBO Member

Jiří Lukas

University of Copenhagen | Denmark

EMBO 2002 | Council 19–21 | Council 22–24

Mechanisms and dynamics of genome surveillance

We study spatial and temporal dynamics of chromosomes during the mammalian cell cycle and after DNA damage with an emphasis on how these mechanisms are subverted in cancer and other diseases associated with genome instability. My long-term interests also include high-content microscopy screens for genome caretakers and real-time imaging of signalling and repair reactions induced by DNA damage.

Keywords: DNA damage response / chromatin biology / live cell imaging / nuclear dynamics / cell cycle checkpoints

Subject area(s): Cell Cycle | Genome Stability & Dynamics