EMBO Member
Jiří Lukas
EMBO 2002 | Council Member 19–21 | Council Member 22–24
University of Copenhagen, Denmark
Mechanisms and dynamics of genome surveillance
We study spatial and temporal dynamics of chromosomes during the mammalian cell cycle and after DNA damage with an emphasis on how these mechanisms are subverted in cancer and other diseases associated with genome instability. My long-term interests also include high-content microscopy screens for genome caretakers and real-time imaging of signalling and repair reactions induced by DNA damage.
Keywords
DNA damage response / chromatin biology / live cell imaging / nuclear dynamics / cell cycle checkpoints