Gene regulation in human development, disease & evolution
Research in our laboratory is focused on understanding how regulatory information encoded by the genome is integrated with the transcriptional machinery and chromatin context to allow for emergence of form and function during human embryogenesis and evolution, and how perturbations in this process lead to disease.
Keywords
Cell type-specific gene expression / enhancer function / retrotransposon regulation / transcription / craniofacial development / neural crest