Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Johannes Zuber

Research Institute of Molecular Pathology (IMP), Vienna | Austria

EMBO 2022

Finding and understanding cancer dependencies

Our lab develops and applies functional-genetic approaches (advanced CRISPR- and RNAi-based screening methods, chemical-genetic protein degradation, time-resolved transcriptomics) to identify and mechanistically study dependencies in cancer and tumor-associated immune cells. In current projects, we are applying these tools to decipher the regulation and function of transcriptional master regulators and to explore rational combination therapies.

Keywords: Cancer biology / molecular medicine / functional genetics / CRISPR / RNAi / genetic screens / transcriptomics / transcription factors / cancer dependencies / cancer immunity / combination therapies

Subject area(s): Chromatin & Transcription | Differentiation & Death | Genomic & Computational Biology | Molecular Medicine