
EMBO Member
John C. Marioni
EMBO 2021
EMBL-EBI, Cambridge (Hinxton), United Kingdom
Computational single cell biology
My group uses computational tools to understand the mechanisms that underlie cell fate decisions. Since such decisions are ultimately made at the single-cell level, this requires assaying molecular characteristics of individual cells, a process made possible by advances in the field of single-cell genomics. Our group develops statistical methods for analysing data from such experiments and uses these to study early development and cancer.
Keywords
Computational biology / genomics / single-cell genomics / statistics