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EMBO Member

John C. Marioni

EMBL-EBI, Cambridge (Hinxton) | United Kingdom

EMBO 2021

Computational single cell biology

My group uses computational tools to understand the mechanisms that underlie cell fate decisions. Since such decisions are ultimately made at the single-cell level, this requires assaying molecular characteristics of individual cells, a process made possible by advances in the field of single-cell genomics. Our group develops statistical methods for analysing data from such experiments and uses these to study early development and cancer.

Keywords: Computational biology / genomics / single-cell genomics / statistics

Subject area(s): Genomic & Computational Biology | RNA