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EMBO Member

Jonathon Howard

Yale University, New Haven | United States

EMBO 2004

Molecular mechanics of cell shape and motion

How do molecules make cells? How do cells move? To understand the interaction rules that allow molecules to work together to form highly organized and dynamic cellular structures, we use highly sensitive techniques to visualize and manipulate individual biological molecules. Most of our work focuses the microtubule cytoskeleton. Our systems include cilia and flagella, neuronal morphology and mitosis.

Keywords: Morphology / motor proteins / cytoskeleton / microtubules / mechanical signaling / dendrites and neurons / kinesin / cilia and flagella

Subject area(s): Cell & Tissue Architecture | Proteins & Biochemistry | Structural Biology & Biophysics