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EMBO Member

Jordi Casanova

Institut de Recerca Biomèdica (IRB), Barcelona | Spain

EMBO 2000

Life and plasticity of Drosophila progenitor cells

We focus our research on the Drosophila adult progenitor cells as a paradigm for cell plasticity, multipotency and reprogramming in vivo. These issues are extensively studied in biomedicine research, but, in my opinion, we lack a critical biological knowledge due to an insufficient study of these issues in the physiological context in the full organism. To this end, we are exploiting naturally occurring progenitor cells in the Drosophila larva.

Keywords: Progenitor cells / cell plasticity / stress / cell death / polyploidy / metamorphosis / Drosophila

Subject area(s): Cell & Tissue Architecture | Development | Differentiation & Death