Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Judith Klumperman

University Medical Centre, Utrecht | Netherlands

EMBO 2008

The endo-lysosomal system in health and disease

My group studies transport of lysosomal proteins and lysosome biogenesis in health and disease. We investigate the role of components of the HOPS and CORVET complex, which are increasingly recognized as causative genes for myopathies, neurological and multisystem disorders. We also want to understand how lysosomes contribute to cancer metastasis and cancer cell death.

Keywords: Membrane traffic / endocytosis / lysosomes / electron microscopy / live cell imaging

Subject area(s): Cellular Metabolism | Cell & Tissue Architecture | Membranes & Transport