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EMBO Member

Jürg Bähler

University College London | United Kingdom

EMBO 2010

Genome regulation in fission yeast

We study transcriptional and post-transcriptional gene expression programmes during cellular proliferation, quiescence/ageing, and stress response using Schizosaccharomyces pombe as a model system. We apply multiple genetic and high-throughput approaches for systems-level understanding of regulatory networks and complex relationships between genotype, phenotype, and environment, including the roles of genome variation and evolution, transcriptome regulation, and non-coding RNAs.

Keywords: Gene expression / transcriptome / non-coding RNA / S. pombe / chronological lifespan

Subject area(s): Chromatin & Transcription | RNA | Systems Biology