Genome regulation in fission yeast
We study transcriptional and post-transcriptional gene expression programmes during cellular proliferation, quiescence/ageing, and stress response using Schizosaccharomyces pombe as a model system. We apply multiple genetic and high-throughput approaches for systems-level understanding of regulatory networks and complex relationships between genotype, phenotype, and environment, including the roles of genome variation and evolution, transcriptome regulation, and non-coding RNAs.
Keywords
Gene expression / transcriptome / non-coding RNA / S. pombe / chronological lifespan