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EMBO Member

Juri Rappsilber

Technische Universit├Ąt, Berlin | Germany

EMBO 2021

Structural biology in cells, by mass spectrometry

We aim to understand molecular processes in structural detail within their cellular context. For this we pioneer proteomic technologies, primarily using crosslinking to capture protein-protein interactions, which we then identify at residue-level resolution by mass spectrometry.

Keywords: Crosslinking mass spectrometry / in-cell data / structural interactomics / co-expression analysis / uncharacterised proteins / structural proteomics

Subject area(s): Proteins & Biochemistry | Structural Biology & Biophysics | Systems Biology

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