Structural biology in cells, by mass spectrometry
We aim to understand molecular processes in structural detail within their cellular context. For this we pioneer proteomic technologies, primarily using crosslinking to capture protein-protein interactions, which we then identify at residue-level resolution by mass spectrometry.
Keywords
Crosslinking mass spectrometry / in-cell data / structural interactomics / co-expression analysis / uncharacterised proteins / structural proteomics