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EMBO Member

Karim Labib

University, Dundee | United Kingdom

EMBO 2010 | YipC 14–17 | YipC 17–19 | InstgC 22–25

Chromosome replication and genome integrity

The main interest of my lab is study the mechanisms and regulation of chromosome replication, in order to determine how proliferating eukaryotic cells preserve the integrity of their genomes and maintain epigenetic information. Our work is focused on trying to understand the structure, function and regulation of the eukaryotic replisome.

Keywords: DNA replication / checkpoints / chromatin / yeast / genome integrity / worm / ubiquitin / Cdc48

Subject area(s): Cell Cycle | Genome Stability & Dynamics | Proteins & Biochemistry