EMBO Member
Keith Gull
EMBO 2010
University of Oxford, United Kingdom
Trypanosome cytoskeleton and antigenic variation
My research focuses on how the microtubule cytoskeleton of African trypanosomes is built and contributes to shape, form and motility of these parasites. In addition I am interested in the molecular and cell biological mechanisms controlling antigenic variation in African trypanosomes. We have a particular focus on the mechanisms underpinning monoallelic expression of the many variable antigen genes.
Keywords
Trypanosome / cytoskeleton / flagella / cilia / microtubule / antigenic variation / Pol1 / nuclear bodies