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Single cell and synthetic genomics of blood

My lab is interested in adult blood formation, one of the most sophisticated and biomedically relevant regenerative systems. We develop and apply novel genomics-based methods to approach this topic from new angles. Recently, we have focused on the analysis of clonal heterogeneity in leukemia and healthy hematopoiesis, as well as on the cis-regulatory encoding of lineage-specific gene expression during stem cell differentiation.