EMBO Member
Semmelweis University, Budapest | Hungary
EMBO 2024
We study the structure and function of ion channels focusing on two proteins: the CFTR chloride channel and the TRPM2 cation channel. Our experimental approaches include real-time recording of ionic currents of single ion channel proteins and of large channel populations using the patch-clamp technique, kinetic analysis of current time courses, site-directed mutagenesis, protein biochemistry and structural methods, as well as mathematical modeling.
Keywords: Ion channels / cystic fibrosis / enzyme kinetics / structure-function / gating / CFTR / TRPM2
Subject area(s): Proteins & Biochemistry | Molecular Medicine | Membranes & Transport