Search    Show all


1 People found

filters applied:

Details

1 / 1

EMBO Young Investigator

Leila Akkari

Netherlands Cancer Institute, Amsterdam | Netherlands

YIP 2021

Macrophage dynamics in cancer progression

Our group studies the microenvironment-mediated mechanisms of tumor maintenance, therapeutic resistance and recurrence in brain and liver malignancies, in order to to identify exploitable therapeutic vulnerabilities in macrophage heterogeneous subsets. Using mouse models of glioma and hepatocellular carcinoma combined with lineage tracing systems, we explore and target the functions of resident versus infiltrating macrophages.

Keywords: Tumor microenvironment / macrophages / therapy / mouse models / anti-tumor immunity

Subject area(s): Cell & Tissue Architecture | Immunology | Signal Transduction

EMBOwords