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EMBO Member

Leszek Kaczmarek

Nencki Institute of Experimental Biology, Warsaw | Poland

EMBO 2000 | FelC 04–07 | Council 10–12 | Council 13–15

Molecular biology of the brain-mind connection

Our laboratory aims at an understanding of molecular and cellular foundations of brain-mind connection both under physiological (learning and memory) and pathological (neuropsychiatric: addiction, schizophrenia, epileptogenesis, autism) conditions. Our discovery over 25 years ago that learning produces a robust and transient activation of c-fos gene expression led us to study today extracellular proteolysis at the synapse in health and disease.

Keywords: Neuronal plasticity & neuropsychiatric disorders / gene expression in the brain / extracellular matrix / learning & memory

Subject area(s): Chromatin & Transcription | Molecular Medicine | Neuroscience