Cancer metabolism and phosphoinositide signaling
The Cantley lab employs a wide range of techniques in its investigation of cancer metabolism and phosphoinositide signaling. From genetically engineered mouse model systems and human cancer cell lines to metabolomic, transcriptomic and proteomic analyses, to the biochemical characterization of enzymes, we use a variety of tools and an interdisciplinary approach to paint a more complete picture of cancer and develop therapies based on novel enzyme targets and other promising new approaches. [ from http://cantleylab.weill.cornell.edu ]
Keywords
PI3-kinase signalling / cancer cell metabolism / insulin signalling / drug development / phosphoinositides / protein kinase pathways