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EMBO Young Investigator

Luca Tiberi

University, Trento | Italy

YIP 2021–2025

Modeling brain cancer with human organoids

In the last four years, our team has developed a novel brain cancer organoid model. Indeed, we generated human iPSC-derived medulloblastoma cancer organoids by introducing genetic alterations found in human cancer. Now, we are taking advantage of this technology to produce novel brain cancer organoids that we are then using to address fundamental cancer biology questions.

Keywords: Brain organoids / neural stem cell / brain cancer

Subject area(s): Cell & Tissue Architecture | Molecular Medicine | Neuroscience