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EMBO Member

Lukas Kapitein

University, Utrecht | Netherlands

EMBO 2023

Microtubules and intracellular transport

We study the mechanisms by which cells establish and maintain their precise shape and intracellular organization. We particularly focus on the microtubule cytoskeleton of neurons, whose complex spatial architecture and polarized organization into axons and dendrites are crucial for proper functioning. To understand how microtubule organization underlies (polarized) transport, we develop and apply multiple forms of advanced (super-resolution) light microscopy.

Keywords: Intracellular transport / motor proteins / cytoskeleton / neurons / cell polarity / super-resolution microscopy / optogenetics

Subject area(s): Cell & Tissue Architecture | Membranes & Transport | Neuroscience | Structural Biology & Biophysics