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EMBO Member

Lukas Sommer

University, Zurich | Switzerland

EMBO 2026

Neural crest stem cells in health and disease

My lab investigates the regulation of neural crest stem cell biology during embryonic development and how neural crest stem cell programs are implicated in skin wound healing and skin cancer. We study mechanisms controlling cell fate decisions, how peripheral nerves reactivate embryonic programs during skin repair, and how neural crest stem cell pathways are hijacked in skin tumor formation, metastasis, and therapy response.

Keywords: Neural crest / stem cells / skin / wound healing / tissue regeneration / tumorigenesis / melanoma / squamous cell carcinoma

Subject area(s): Development | Molecular Medicine | Neuroscience

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