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EMBO Young Investigator

Mahima Swamy

University, Dundee | United Kingdom

YIP 2023–2026

Immune interactions at the intestinal epithelium

Within the single layer of epithelial cells lining the gut are an enigmatic group of unconventional T cells called intraepithelial lymphocytes (IEL). Our lab aims to understand how IEL communicate with epithelial and other immune cells — to protect against infection, aid in the dietary regulation of the gut, and maintain tolerance. We are also exploring the Crohn's disease-associated kinase LRRK2 in intestinal immune function and inflammatory bowel diseases.

Keywords: Intestinal immunity / infection / antigen receptor signalling / quantitative proteomics / immunometabolism / inflammatory bowel diseases

Subject area(s): Signal Transduction | Molecular Medicine | Microbiology, Virology & Pathogens | Immunology