
EMBO Member
Manuel Irimia
EMBO 2025
Former EMBO Young Investigator (2018)
Transcriptomics of development and evolution
My lab focuses on cell- and tissue-specific transcriptomes. How are they encoded in the genome? How are they generated during embryogenesis? How do they impact cell function in adult organisms? How do they evolve and how they impact evolution? We study mechanisms that expand transcriptomic diversity, such as alternative splicing and gene duplication, combining computational and experimental approaches using in vitro and in vivo systems.
Keywords
Transcriptomics / evolution / alternative splicing / microexons / Amphioxus genomics