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Portrait of Manuel Irimia

EMBO Member

Manuel Irimia

EMBO 2025

Former EMBO Young Investigator (2018)

Universitat Pompeu Fabra, Barcelona, Spain

Transcriptomics of development and evolution

My lab focuses on cell- and tissue-specific transcriptomes. How are they encoded in the genome? How are they generated during embryogenesis? How do they impact cell function in adult organisms? How do they evolve and how they impact evolution? We study mechanisms that expand transcriptomic diversity, such as alternative splicing and gene duplication, combining computational and experimental approaches using in vitro and in vivo systems.

Transcriptomics / evolution / alternative splicing / microexons / Amphioxus genomics