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EMBO Member

Marc Lecuit

Institut Pasteur, Paris | France

EMBO 2017 | GinC 19–23

Microbial invasion and within-host dissemination

Systemic infections result from the invasion of hosts by microbial pathogens. Our research focuses on (i) deciphering the cell biology of microbial translocation across host barriers, (ii) studying the impact of microbial portal of entry on microbial fate, dissemination and host responses, (iii) harnessing microbial biodiversity to identify novel virulence factors and (iv) discovering new host factors predisposing to invasive infections.

Keywords: Microbial pathogenesis / cell biology / tissue biology / innate immunity / intestine / placenta / brain / genomics

Subject area(s): Cell & Tissue Architecture | Immunology | Microbiology, Virology & Pathogens | Molecular Medicine