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EMBO Member

Marco Muzi-Falconi

Università degli Studi, Milano | Italy

EMBO 2014

Maintenance of genome integrity in eukaryotes

My work is focused on the mechanisms controlling DNA replication, recombination and repair, and cell cycle progression. We are particularly interested in the connections between chromatin structure, translesion polymerases, nucleases that process damaged DNA and DNA damage checkpoint activation. Recently, we have extended our studies to RNase H function following incorporation of rNTPs within genomic DNA and in promoting mismatch repair.

Keywords: DNA repair / checkpoints / replication / DNA damage / genome stability

Subject area(s): Cell Cycle | Genome Stability & Dynamics