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EMBO Member

Margaret C. Frame

University of Edinburgh | United Kingdom

EMBO 2009

Signalling in cancer

My research is aimed at understanding the signalling pathways that drive cancer and promote invasion and metastasis. We are developing quantitative intra-vital imaging approaches to study the responses to genetic- or drug-based interventions. A key goal is to translate our work, such that we understand how the evolution of cancer driver pathway networks and tumour/host interactions in pre-clinical models and in patients promotes metastasis and therapeutic resistance.

Keywords: Cancer biology / disease modelling / cell adhesions / signalling / imaging / discovery science

Subject area(s): Molecular Medicine | Proteins & Biochemistry | Signal Transduction