EMBO Member
Margaret C. Frame
EMBO 2009
University of Edinburgh, United Kingdom
Signalling in cancer
My research is aimed at understanding the signalling pathways that drive cancer and promote invasion and metastasis. We are developing quantitative intra-vital imaging approaches to study the responses to genetic- or drug-based interventions. A key goal is to translate our work, such that we understand how the evolution of cancer driver pathway networks and tumour/host interactions in pre-clinical models and in patients promotes metastasis and therapeutic resistance.
Keywords
Cancer biology / disease modelling / cell adhesions / signalling / imaging / discovery science