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EMBO Member

Maria Falkenberg

Göteborg University | Sweden

EMBO 2024

Human mitochondrial DNA maintenance

My laboratory studies DNA maintenance in mammalian mitochondria. We use in-vitro biochemistry, structural biology, and cell biology to explore the underlying enzymatic processes. We also investigate the molecular consequences of disease-causing mutations affecting mitochondrial DNA replication and work on developing new, rational therapeutic approaches.

Keywords: Mitochondria / DNA replication / transcription / mitochondrial DNA synthesis / S7 noncoding RNA

Subject area(s): Membranes & Transport | Genome Stability & Dynamics | Chromatin & Transcription