Tau and synuclein aggregates in neurodegeneration
My group is interested in understanding the mechanisms leading to neurodegeneration in diseases with tau and alpha-synuclein aggregation known as tauopathies and synucleinopathies such as Alzheimer's disease, Progressive Supranuclar Palsy, Frontotemporal dementia, Parkinson's and dementia with Lewy bodies. The aim is to identify targets for therapy and to produce models where mechanisms of disease can be investigated and treatments tested.
Keywords
Synuclein / synucleinopathies / Parkinson's Disease / microtubule associated protein tau / tauopathies / frontotemporal dementia