Geo-immunology and vaccine hypo-responsiveness
Combining challenging field studies, clinical trials in Africa and Asia, as well as controlled human infection model with cutting edge immunological technologies available in our lab at LUMC, our work aims at gaining in-depth understanding of the human immune system. Through this we study how environmental factors (among others, parasites) shape the immune system that impacts vaccine responses and disease profiles.
Keywords
Immune regulatory network / innate immune cells / systems immunology / controlled human infection model / parasitic infections / vaccines / mass cytometry