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EMBO Associate Member

Mark A. Dawson

Peter MacCallum Cancer Centre, Melbourne | Australia

EMBO 2021

Epigenetic regulation in development and cancer

My laboratory studies the basic biological mechanisms by which chromatin complexes and transcriptional regulators coordinate cell fate decisions in normal development and cancer. Areas of interest include understanding the molecular mechanisms that (i) initiate cancer, (ii) sustain malignant stem cells, and (iii) enable therapeutic resistance. Our aim is to use these insights to develop novel therapies that can transition into the clinic.

Keywords: Hematopoiesis / cancer / epigenetics / leukemia / transcription / chromatin / cancer stem cells

Subject area(s): Chromatin & Transcription | Molecular Medicine