Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Mark S. Bretscher

Cambridge | United Kingdom

EMBO 1974

The endocytic cycle and cell locomotion.

My work centered around the mechanism of how animal cells migrate and how this may depend of the endocytic cycle. Membrane internalised by coated pits is returned to the cell's surface at its leading edge: this may provide a mechanism for moving the cell's feet from the rear to the front for reuse. Also, because of the selective nature of the membrane internalised, their return to the front leads to a striking asymmetry of surface proteins.

Keywords: Membrane structure / cellular organisation

Subject area(s): Cell & Tissue Architecture | Membranes & Transport