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EMBO Member

Martin Beck

MPI für Biophysik, Frankfurt | Germany

EMBO 2021

Molecular sociology

Functional cellular modules have often been characterised in vitro. However, relatively little is known about their interplay and spatio-temporal arrangement in the context of living cells, i.e. their 'molecular sociology'. We use integrative, in-situ structural biology techniques to study the structure, function and assembly of very large macromolecular complexes in their native environment.

Keywords: Nuclear pore complexes / protein complex biogenesis / in-situ structural biology / mass spectrometry / imaging / cryo electron tomography

Subject area(s): Membranes & Transport | Proteins & Biochemistry | Structural Biology & Biophysics

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