
EMBO Young Investigator
Martin Guilliams
YIP 2020–2024
VIB - Flanders Institute for Biotechnology, Ghent, Belgium
Myeloid cells in liver homeostasis & regeneration
Our research focuses on the functional specialization of liver macrophages and on the cell-cell interactions with their niche, constituted of hepatocytes, stellate cells and endothelial cells. We are particularly interested in: (i) identifying the transcription factors that imprint the liver-specific identity, (ii) identifying the cell-cell circuits that maintain homeostasis and (iii) understanding the mechanisms that instruct liver regeneration.
Keywords
Macrophage / Kupffer cell / niche / development / tissue-imprinting / regeneration / liver