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EMBO Young Investigator

Martin Jinek

University, Zurich | Switzerland

YIP 2016

RNA biology and genome editing

My research focuses on molecular architecture and mechanisms of protein-RNA complexes involved in regulating gene expression and in genome defence. Using structural, biochemical and functional approaches, we investigate CRISPR-Cas systems to develop novel genome editing technologies. We also explore RNA-targeting antiviral mechanisms in innate immunity and multi-subunit complexes involved in eukaryotic RNA metabolism and ribosome biogenesis.

Keywords: Structural biology / RNA / macromolecular complexes / gene expression / CRISPR-Cas / RNA metabolism / genome editing

Subject area(s): Proteins & Biochemistry | RNA | Structural Biology & Biophysics