
Microbial cell-cell interactions
Microbes interact with other cells in most ecological settings. We study macromolecular machines mediating cell-cell interactions, with a focus on mechanism, structure and evolution. We integrate information from the molecular to the cellular and intercellular scale, by combining cryo-electron tomography with other imaging methods and functional assays. Our main topics are 'Contractile Injection Systems' and 'Asgard archaea'.
Keywords
Microbial cell-cell interactions / cytoskeleton / multiscale imaging / macromolecular machines / electron microscopy / cryo-electron tomography / archaea