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EMBO Associate Member

Masatoshi Takeichi

RIKEN Center for Biosystems Dynamics Research (BDR), Kobe | Japan

EMBO 2009

Regulation of cell-cell adhesion and morphogenesis

Our laboratory studies the mechanisms by which animals cells organize themselves into complex tissues. We focus on a group of intercellular adhesion molecules, cadherins, and associated signaling systems. We analyze their roles in epithelial and neural morphogenesis, cell migration, and cancer invasion. Our recent studies also include the roles of microtubule minus-end binding proteins in cellular behavior and morphogenesis.

Keywords: Cell adhesion / cadherin / catenin / cytoskeleton / morphogenesis / microtubule minus-end / CAMSAP

Subject area(s): Cell & Tissue Architecture | Development | Neuroscience