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EMBO Member

Matthias Peter

ETH, Zurich | Switzerland

EMBO 2001

Ubiquitin-dependent regulation of cell growth and division

We are using biochemistry, structural biology, modern yeast genetics, RNAi-screening, dynamic and quantitative light microscopy and microfluidic technology to tackle the following main topics both in yeast and mammalian cells: (i) function and regulation of cullin-based E3-ubiquitin ligases; (ii) mechanisms and regulation of selective autophagy pathways; (iii) dynamic and quantitative analysis of signal transduction pathways in single cells

Keywords: Cell cycle / growth control / cell polarity / MAP-kinase signalling / ubiquitin-dependent regulation / selective autophagy

Subject area(s): Membranes & Transport | Proteins & Biochemistry | Cell & Tissue Architecture